This may be the result of either previously undiagnosed or untreated Addison's disease, a disease process suddenly affecting adrenal function (such as bleeding from the adrenal glands in Waterhouse–Friderichsen syndrome), suddenly stopping intake of glucocorticoids or an intercurrent problem (e.g. It is a constellation of symptoms (caused by insufficient levels of the hormone cortisol) that indicate severe adrenal insufficiency. ![]() Addisonian crisis and acute adrenal insufficiencyĪ chart measuring a change in plasma cortisol cycle (mcg/dl) over 24 hoursįever, lethargy, hyperkalemia, hyponatremia, hypotension, diarrhea, vomiting, convulsions Īddison's disease, Congenital adrenal hyperplasia, Waterhouse–Friderichsen syndrome, hypopituitarismĪdrenal crisis is a potentially life-threatening medical condition requiring immediate emergency treatment.
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